Melioidosis Real-Time PCR Kit
Melioidosis, caused by the environmental gram-negative bacterium Burkholderia pseudomallei, is a tropical disease often manifesting as severe sepsis. In tropical regions where melioidosis is prevalent, the mortality rate for sepsis and melioidosis is alarmingly high with 40-80% of patients exhibiting bacteremia and pneumonia, underlining the urgent need for effective diagnostic solutions. Currently, available methods for identifying melioidosis patients are limited, contributing to under recognition and misdiagnosis of this fatal pathogen.
In addressing this critical healthcare challenge, the ready-to-use real-time PCR kit for B. pseudomallei detection is a significant breakthrough. Its purpose is to enhance the diagnosis process for melioidosis suspected patients. The kit provides high sensitivity and quick diagnosis capabilities which are essential for timely patient management and clinical decision-making, enabling prompt administration of appropriate antimicrobial agents for melioidosis. This not only reduces disease severity but also impacts the mortality rate and the overall cost of hospital care.
The gold standard for diagnosis is bacterial culture but has a low sensitivity of 60% and a low throughput rate, which does not meet the demands for quick and accurate detection in melioidosis cases. This technology addresses this gap by offering a rapid, highly sensitive diagnostic tool that is crucial to reduce severe infections that lead to high mortality rate.
The technology owner is seeking collaborations with medical institutions (particularly those specializing in infectious disease diagnosis and treatment), device manufacturers capable of producing and distributing the kit at scale, research institutions and academic organizations.