TECH OFFERS

Neurological diseases are the second leading cause of death. CT scans have been used as the primary modality to diagnose brain abnormalities such as Intracranial Haemorrhage (ICH) and neurodegeneration. Radiologists usually have to deal with an overwhelming scan backlog and writing radiology reports is a time consuming process. Manual segmentation of lesions is tedious and existing heuristics have been shown to overestimate lesion volumes. Clinicians are also wary of the ‘black box’ nature of deep learning models. Hence, an automated tool in the workflow could substantially improve clinical productivity and interpretability is crucial to build trust with clinical stakeholders. Our proposed technology is an AI solution that automates ICH detection and brain tissue segmentation on CT scans, producing accurate volumetric information to assist triaging. Our technology also comes with a set of tools to interact with the AI models and generate reports easily. Moreover, we strengthen our AI transparency with interpretable models. Our platform also focuses on model robustness tests to assure AI safety.   Our core technology is our trained deep learning detection and segmentation models. Our web user interface allows visualization of the medical images and the AI predictions. Users can upload their scan using our web interface (deployed locally or in a private cloud) and obtain the results and report instantly. In the report section, users can also customize the layout of the radiology report to suit their workflow. We look forward to deploying our solution in healthcare institutions that work with CT scanners. Our technology can be deployed locally or on a secured cloud platform and integrated with local PACS systems. Our current focus area is in neurology but our solutions can be generalisable across modalities and tasks. The size of the AI medical imaging market is projected to be 20.9 billion USD in 2030. The addressable market size in Neurology and CT is 2.85 billion USD (13.6%). Our AI solution is tailored to learn Asian population brain anatomical data, which is unique in the market, therefore we are targeting to serve the Asia Pacific market which is estimated to be around 769 million USD (27%). While some available products offer solution to predict whether ICH exists in the scan, our technology automates ICH segmentation that allows accurate calculation of the lesion volume from CT scans. Secondly, most available products in the market rely on MRI scans for brain tissue segmentation, but our technology allows fast inference on CT scans. Our technology is also able to perform Alzheimer’s Disease detection using CT scans. Crucially, our solution provides ways to identify drifts, quantify uncertainty and explain model decisions in discriminative tasks, which can help build trust with clinicians. Healthcare, Telehealth, Medical Software & Imaging

Digitalisation is a global trend with digital twin technology increasingly adopted in various industrial segments including smart factories and plants, digital facility management and operation & maintenance, building and construction, etc. Rapid generation of digital twin of physically existing is desired. Conventionally, digital twin is mainly generated using design software which requires professional modellers to spend substantial design time pending on the complexity of the physical twin (to be constructed) and the manpower available. Building information modelling (BIM) is increasingly used as a representation for the digital twin. For existing environments, scan to BIM technology and authoring software products are used for the process of reconstructing of BIM models from LiDAR scanned point clouds. This manual process is typically time consuming, tedious and error prone. Often, meshed models are used for visualization purpose of the digital twin. Our innovation is an integrated solution being able to autonomously scan physical environments using robotised LiDAR cameras, automatically stitch scanned point clouds using in-house developed software algorithms, automatically recognise BIM components as well as mechanical & electrical plumping using our innovated AI techniques, and automatically convert the reconstructed BIM (not mesh models) from point cloud in IFC4.0. The solution can significantly reduce manpower needs and improve productivity from days/weeks down to hours. Ideal collaboration partners include but are not limited to builders, government agencies, smart city or smart factory planners, construction project management service providers, architecture, engineering and construction companies.   Building & Construction, Safety, Oil & Gas，etc. are relevant Industries. Potential applications include Audit & Inspection, Altering & Addition, Construction Project Management, Smart City, Smart Factory, Smart Process Plant, Smart Power Grids, etc.  A cloud-based solution can be marketed as a product for this technological innovation. Automatic BIM conversion (not mesh models) from LiDAR scanned point clouds is a significant improvement over the current manual conversion; and Rapid BIM reconstruction (not mesh models) in IFC 4.0 format is another UVP with substantial productivity improvement. Infocomm, Green ICT

Coronary artery disease (CAD) is the leading cause of death worldwide. Computed Tomography Coronary Angiography (CTCA), as a non-invasive alternative to invasive catheterized coronary angiography, has emerged as a recommended first-line investigation for CAD. However, the current practice of generating reports involves a time-intensive process, with CT specialists spending 3-6 hours annotating scans. Furthermore, there is a lack of effective tools for analysing coronary calcium scores, stenosis severity, and plaque characterization. This AI driven platform is for CT data processing that provides a streamlined 'one-stop' solution spanning from diagnosis to clinical management and prognosis. Its key features include: AI-driven platform for CTCA, catering to clinical, research, and industrial applications. Large, shareable, de-identified, Personal Data Protection Act-compliant real-world CT data. Precision toolkits for anonymization, coronary calcium scoring, epicardial adipose tissue (EAT), stenosis severity assessment, plaque quantification, CT fractional flow reserve (FFR), and reporting. The platform’s highly automated features assist physicians in interpreting and synthesizing large volumes of CT data, while minimizing bias, increasing reproducibility, and providing numerical insights in a graphical manner. It offers a comprehensive ‘one-stop’ solution for diagnosis and clinical management of CAD. Seamless integration: The DICOM-compliant parser ensures compatibility with diverse CT scanners without interfering with hospitals’ original workflow processes. AI-driven workflow: It supports fully automated analysis, including deep learning-based segmentation of the coronary artery tree, extraction of artery centrelines, tracking and acquisition of cross-section lumen images, artery labelling, stenosis and plaque detection, and quantification with high accuracy within minutes.  Comprehensive modules for CAD assessment: The technology offers a comprehensive assessment of coronary calcium score, EAT, stenosis, and plaque phonotypes. Mixed Asian registry database: It houses a vast repository of multi-ethnic imaging and non-imaging data, serving as a valuable resource for research and analysis. Annotation by SCCT-certified experts: All annotations are performed and quality-checked by experts certified by the Society of Cardiovascular Computed Tomography (SCCT). Secure and reliable data platform: The data platform is certified by the Ministry of Health Singapore, ensuring the safety and reliability of data access. The technology can be applied across various industries: Software as a clinical service for healthcare institutions: It provides comprehensive CAD assessment and personalized treatment as a software-as-a-service (SaaS) solution for healthcare institutions. Pharmaceuticals: It enables objective and quantitative measurement of the effectiveness of treatments. MedTech and digital health industry: By harnessing state-of-the-art technology and big data capabilities, it provides the development of customized foreground intellectual property, addressing the specific needs of individual companies. Local MedTech industry development: It offers tailored solutions designed specifically for small and medium-sized enterprises (SMEs) and startups, empowering them to compete globally, foster innovation in product development and services that align with market demands, and enhance patient care. It provides a thorough evaluation of the coronary arteries using deep learning algorithms and patented post-processing technologies. It serves as a ‘one stop’ platform that spans from diagnosis to clinical management and prognosis, and aiding in predicting therapy response in the pharmaceutical industry. Superior diagnostic performance: The AI toolkits deliver exceptional accuracy, surpassing 90%, while processing the data within minutes. This remarkable speed is 20 times faster than the standard diagnostic and reporting process, enabling efficient and timely decision-making. Unparalleled big data repository: The platform houses the largest mixed Asian CAD registry, comprising 5,000 patients (n=3 million images). This vast collection contains a wealth of real-world imaging and non-imaging data, representing a unique and invaluable resource that is unmatched elsewhere. Trusted ground truth: Every CT scan has been meticulously annotated and quality-checked by SCCT-certified experts. This rigorous process ensures the accuracy and reliability of the data, establishing a safe and dependable foundation for clinical decision-making. Healthcare, Telehealth, Medical Software & Imaging

For many years, gas detection applications in industries have predominantly relied on single point detectors, which are applicable in many industries covering a wide market sector.   Starting from the year 2010 and onwards, open path line detectors have gained significant recognition and popularity due to their cost-effectiveness and ability to cover larger areas, thereby enhancing safety measures.  More device options are now on the market.   However, all of these devices have the inherent problems of false alarms due to environmental interference, such as rain and snow. A waveform matching technology – multi order laser emitting spectrum (MOLES) was invented. This cutting-edge technology ensures specific gas detection, it only detects when specific gas is detected, and eliminates all false alarms caused by environmental interference.   By gathering industrial inputs and feedbacks, improvements and user-desired features are incorporated into this invention, to enhance its overall performance, reliability and solving many user problems on site, such as no display, alignment problems, and calibration.  This breakthrough innovation will provide a more efficient and reliable gas detection solution for industries, safeguarding their operations and personnel. This Open Path Gas Detection technology is Laser Gas specific with: Customised micro-controller based CPU With built-in automatic calibration capability With built-in visible laser for ease of installation and alignment With built-in display for improved ease of use at site; single man operation instead of two With built-in audible siren for alarm warning Ideal collaboration: B2B – Gas detection manufacturers B2C – Gas detector users from the Chemical, Petro-Chemical, Oil & Gas industries This open path gas detection devices are applicable in a wide market sector, including Oil and Gas, Chemicals, Water and Wastewater, Marine, Transport, Semi-conductor, Food and beverage, and Energy.   According to a research report published by Spherical Insights & Consulting, the Global Gas Detection Equipment Market Size is to grow from USD 4.25 billion in 2022 to USD 13.87 billion by 2032, at a Compound Annual Growth Rate (CAGR) of 12.56% during the projected period. Additionally, increased exploration and production by several oil corporations, such as the National Offshore Oil Corporation of China and the Oil & Natural Gas Corporation of India, is increasing demand for the region's gas detection equipment market. The Asia Pacific gas detection equipment market is expected to be led by China. North America is predicted to expand the fastest during the forecast period. The abundance of a big oil and gas pipeline network, as well as oil and gas refinery operations, in nations such as the United States and Canada, predicts significant market growth. Though Open Path gas detection devices may constitute a small percentage in the gas detection market, estimated <5%, it has fast been recognised in recent years to be more cost-effective option, and many new installations and projects nowadays, specified in their constructions, to have more open path devices for improved and effective gas leaks safety preventions.  Therefore, it is projected that the market potential for this open path devices is encouraging.  This open Path Gas Detection Device is: More cost effective than existing point detection devices Extra long distance coverage ~200m Enhance reliability and performance as compared to existing open path gas detection devices Eliminates false alarms due to environment interferences Improved ease of use; installation and alignment Open Path, Gas Detection, Long Distance, Multi Order Detection, Laser, Oil & Gas Electronics, Sensors & Instrumentation, Green Building, Sensor, Network, Building Control & Optimisation, Environment, Clean Air & Water, Sensor, Network, Monitoring & Quality Control Systems

Lithium ion (Li-ion) battery is now the dominant energy storage system in portable electronics and electric vehicles (EV). The rapid expanding EV is driving the demand for next generation high-energy batteries. Compared to conventional Li-ion batteries with graphite anode, which has a theoretical capacity of 372 mAh/g, lithium-metal batteries can deliver ten times of specific capacity (3860 mAh/g). Theoretically, anode-free batteries can double the energy density in volume compared to Li-ion batteries at the cell level. However, current anode-free batteries suffer from faster capacity decay due to poor lithium plating on Cu foil. To overcome this challenge, the technology owner has developed a liquid electrolyte comprising lithium difluoro(oxalate)borate (LiDFOB) and a carbonate solvent, enabling reversible lithium plating of anode-free lithium metal batteries. This electrolyte ensures good thermal stability with smooth Li plating of counter electrode on the anodic side even at elevated temperatures. It facilitates a capacity retention of above 80% after 100 cycles for an anode-free battery or 80% after 400 cycles for a battery with a Li metal anode. The technology owner seeks collaboration with industrial partners such as battery developers and manufacturers for further co-development and test-bedding of electrolyte and subsequent licensing of this technology for commercialisation. The patented technology is an electrolyte comprising lithium difluoro(oxalate)borate (LiDFOB) dissolving in an organic carbonate solvent that has the following features: High concentration of the LiDFOB in the range of 1.5M to 3M Enable smooth and reversible lithium plating / stripping Good cycling performance and high charging rate Good thermal stability enabling high operating temperature (up to 80 °C) Good electrochemical stability compatible to high voltage cathodes The patented electrolyte can be applied to high-energy lithium ion batteries, which have the following potential applications: Aerospace and aviation (drones and satellites) Electric vehicles (EVs, HEVs) Grid-scale energy storage Backup power systems Enable smooth and reversible lithium plating Higher energy density (about 30% increase in gravimetric capacity) Good thermal stability and cycling performance Enable high-energy-density anode-free lithium metal batteries Lithium ion battery, Electrolyte, LiDFOB Energy, Battery & SuperCapacitor, Chemicals, Polymers, Organic

Algae are very diverse organisms that possess many functional ingredients. With the suitable cultivation know-how and state-of-the-art technology, the applications for algae are limitless. A cleantech start-up focuses on algae as means to provide sustainable solutions to global issues. Most algae companies use a single alga for specific applications. However, the start-up uses its intensive library, breeding and cultivation expertise, and its mass production technology to provide targeted products and solutions for different industries. The start-up is seeking for partners that are interested in exploring algae for their industrial applications, which can include food, medical, or environmental purposes. Possible modes of collaboration include technical consultancy, R&D, process and/or product development.  The start-up offers an “Algae Platform” that consists of the following: Consulting Intensive Strain Library Screening Breeding Technology and Cultivation Expertise Small-Scale Pilot Production Facility Based on the needs of the clients, strains from the library are screened for the targeted products. Following identification of suitable strains, the next step would be a sustainable cultivation method/facility for the algae. This platform assures ongoing consultation between the start-up and its clients so as to achieve the targeted products that the clients desire. At present, the start-up has algae strains that are promising in terms of their protein content, oil content and functional ingredients. Potential applications of leveraing this algal platform technology include but not limited to:  Alternative Protein Biomaterials Dietary Supplements Cosmetics Foods Nutraceuticals Pigments For potential partners, a business benefit can include the opportunities for consultation and identification of suitable algal applications that can benefit their business. This is especially relevant if partners are interested in a more sustainable source of their target products (i.e., alternative protein, biomaterials and functional ingredients). Environmental advantages include negative carbon footprint due to CO2 utilization by algae and less land usage. algae platform, biomass, functional ingredients Life Sciences, Agriculture & Aquaculture

This technology is suitable for companies looking for a probiotics delivery system with increased probiotics viability. Spray-dried probiotic powder derived from this technology can be used as dietary supplements or functional food additives for human and animal consumption. Conventional probiotics often lose viability during shelf storage and upon ingestion, especially during their transit through the gastric region. Our industrially scalable encapsulation technology can improve probiotics’ shelf life and maintain viability during their passage through the human upper gastrointestinal tract. The encapsulated probiotic product achieves qualities of gastroprotection and targeted release in the intestinal region, overall boosting the beneficial effects of probiotics on gut health. Probiotics represent a US$ 58 billion market with immense growth potential, as global consumers are increasingly invested in digestive health and means to enhance the gut microbiome. Our patented technology of encapsulating probiotics involves a modified spray-drying process and is a high-throughput, food-grade, and inexpensive technique applicable to pharmaceutical, food and animal feed sectors. The modified spray drying technique used in this technology is a facile, high-throughput and industrially preferred method to produce environment resistant encapsulation systems. Key advantages of this optimized spray drying process include: High encapsulation efficiency High probiotics viability Achieving a dried product with high powder yield This technology provides four major advantages in probiotics supplementation: Scalability of production Uses food-grade materials and hence renders the advantage of non-toxicity Offers gastroprotection of probiotics in the upper GI tract High viability over shelf-life This technology may be versatilely used for a variety of candidate probiotic microorganisms and can henceforth be applied to many different applications and markets. The encapsulated dry probiotic powder product is: 1. Applicable to both human health product lines and animal feed formulations due to its use of generally regarded as safe (GRAS), non-toxic materials 2. Compatible with incorporation of other active pharmaceutical ingredients alongside probiotics (to promote or enhance desired therapeutic outcomes) 3. Dried probiotic powder is compatible with standard pharmaceutical or dietary supplement dosage formats (e.g. capsules, tablets, or sachets) 4. Dried probiotic powder can be incorporated into functional food or beverage matrices, such as confectionaries, dairy products and instant foods. The probiotics market was valued at US$ 58 billion in 2021 and is projected to grow at a compound annual growth rate (CAGR) of 7.5% through 2030. The market is driven by a rise in health expenditure, an increasing consumer inclination towards preventive healthcare and a growing consumer awareness about the importance of the gut microbiome in influencing human health. So far, probiotics are mainly consumed via dairy-based yogurts (74% of the global retail value of probiotics), while 11% is attributed towards probiotics supplements. The market for probiotic supplements is set to expand rapidly, at a CAGR of 7%, from its market size of US$ 6.5 billion in 2021 (Grand View Research, 2021). Probiotic supplements may be consumed in the form of capsules, chewables/gummies, powders, tablets and softgels. This technology is well-positioned to develop probiotic supplements suitable for these various formats, as the dried powder product can be versatilely incorporated. Besides supplements, there is a growing trend to incorporate probiotics in different foods and beverages. Several examples of innovation here include probiotic ice-creams, probiotic sodas, probiotic beers, probiotic candies, probiotic ice, etc. This technology can be useful to encapsulate and protect probiotics from the external food or beverage matrix and prolong its survivability and functionality. The use of probiotics in animal feed sectors represents another opportunity. The global probiotics in the animal feed market was valued at US$ 4.4 billion in 2020 and is projected to grow at a CAGR of 8.8% through 2026. This technology benefits from having a high-scale and inexpensive production process, which reduces the costs of the encapsulation of probiotics. Using an industry-approved spray drying technique and food-grade materials, our encapsulation system guarantees both safety and scalability. This advanced technology ensures the probiotics' viability as they pass through the upper gastrointestinal tract and reach the gut, providing a remarkable advantage over conventional probiotics. probiotics, encapsulation, viability, shelf-life, spray-drying, high throughput Personal Care, Nutrition & Health Supplements, Healthcare, Pharmaceuticals & Therapeutics, Manufacturing, Chemical Processes, Foods, Ingredients, Processes

Autonomous driving technologies hold promise of substantial manpower savings, but the technology is still not mature enough to remove the driver from the vehicle. This also hinders the deployment of autonomous systems for many business applications as the ROI (Return on Investment) is not justifiable. There are also multiple scenarios, such as firefighting or waste processing, that require the agility offered by a human operator but have worksites that can be harmful. The technology presented here offers a high-fidelity teleoperation solution platform which can control many kinds of vehicles and machinery with high quality video feed at low latency. This technology is particularly useful for autonomous vehicle or machinery related companies that want to release their fleet to the market and have the option to remove the requirement for a safety driver onboard. It is also useful for companies providing heavy machinery, or end users of heavy machinery who seek to remove operators from harmful worksites. Main features and specifications related to the technology are given below: Low end-to-end latency at < 200 msec. Low bandwidth requirement. The technology can work with 4G/5G/Long Range Wi-Fi. Inbuilt smart assistance features and multiple camera view in picture-in-picture format to make operation easy and safe. Motion and haptic feedback for better situational awareness. Potential applications for the teleoperation technology can include, but are not limited to, scenarios like – Autonomous EVs Airport support vehicles Street sweeping vehicles Prime movers Engineering machinery such as forklifts, excavators, and others. The global teleoperation and telerobotic market is expected to reach US$60.9 billion in 2023 and the expected CAGR for the next five years is 14.2%. The TAM (Total Available Market) estimation for 2023 is at US$14 billion in the logistics and autonomous mobility sectors. In Singapore, the SOM (Serviceable Obtainable Market) is estimated at US$ 62.1 million. Telerobotics covers a lot of advantages promised by autonomous mobility and does not have the drawback of uncertainties on maturity level and risks associated. The offered technology solution offers following advantages – The platform can work under 4G, 5G or long-range Wi-Fi. Wide field of view along with multiple camera views in an easy to operate configuration provide the operator with a more natural visual feedback and enhanced awareness. The video stream is further synchronised with haptic feedback to improve operator’s judgment. The platform comes with customizable buttons and controls and can be configured for multiple vehicle types and scenarios. Infocomm, Video/Image Analysis & Computer Vision, Mobility, Geoinformatics & Location-based Services

In the mid-infrared region, gases exhibit absorption spectral features that are typically two orders of magnitude stronger compared to the near-infrared region. This makes the mid-infrared quantum cascade laser (QCL) a highly suitable choice for gas spectroscopy applications. QCLs offer several advantages, including broadband spectral coverage ranging from 3 to 25μm, narrow linewidth, compact size, and robustness, which have contributed to their popularity in various spectroscopic applications. In this context, a portable gas sensor has been developed utilizing self-developed QCL arrays, covering two specific wavelength regimes: 9-10 μm and 13-14 μm. To further enhance the detection sensitivity, an artificial intelligence (AI) algorithm has been integrated into the gas sensor. The incorporation of a hollow-core fiber as a miniaturized gas cell contributes to the overall compactness of the system. By leveraging the capabilities of QCLs, this gas sensor overcomes critical weaknesses associated with existing approaches, particularly their lack of selectivity and inability to differentiate mixtures of gases effectively. We anticipate that this technological innovation will accelerate scientific research progress and prove valuable across various industry sectors. The innovation of this portable gas sensor is mainly in the laser source and beam combining approach. Compared with the commercial QCL products, the developed QCL arrays exhibited wide spectra tuning range, ultra-fast tuning speed, narrow linewidth, and eye-safe average power. To combine the laser beams in the array, a cost-efficient beam combining method has been developed. This method utilizes an aspherical lens and a series of mini mirrors to collimate the individual beams from the laser array. The system is controlled by a LabVIEW program, which simplifies its operation.  After conducting measurements, the AI algorithm automatically calculates the concentration of the target gases. This information is then displayed on the software interface, providing a convenient and user-friendly experience. The gas cell in the sensor employs a hollow-core fiber, which results in a quick analyte charging time of less than 1 minute. Furthermore, the gas sensor utilizes a broadband laser source, enabling simultaneous detection of multiple gases. The performance of the homemade QCL array is notable in terms of lasing peak and transverse mode, making it well-suited as the light source in gas spectroscopic systems. Notably, the gas sensor extends the operation wavelength regime into the ~13-14 μm region, which is advantageous for detecting volatile organic compounds (VOCs) that have strong absorption features in this range. In terms of detection limits, the gas sensor has been evaluated to achieve 940 parts per billion (ppb) for acetylene and 470 ppb for o-xylene. Primary application areas: scientific research, environmental monitoring, and industrial process control. Other areas: Indoor air quality monitoring and oil & gas. The potential products: Mid-infrared photoacoustic gas sensor, QCL-based dual-comb gas sensor, Cavity ring-down gas sensor and liquid sensors.   The global gas sensor market size was valued at USD 2.50 billion in 2021 and is expected to expand at a compound annual growth rate (CAGR) of 8.9% from 2022 to 2030. In this context, the QCL plays a pivotal role as one of the primary light sources in mid-infrared gas spectroscopy applications. Consequently, the QCL-based gas sensor has promising potential in the gas sensor market size. This technology is portable and provides both high selectivity and sensitivity with key benefit lies in three domains: Gas Sensing: this solution enables precise and accurate gas sensing, allowing for the detection and differentiation of multiple trace gases in various environments. Spectroscopy / Instrumentation: With the capability to design and create long-wavelength quantum cascade lasers, our technology is well-suited for advanced spectroscopy and instrumentation applications. IoT (Internet of Things) for Smart-Nation: By integrating this technology into the Internet of Things framework, contribute to building smarter and more efficient nations with improved environmental monitoring and management. The most critical problem of the existing technologies, such as electronic and chemical sensors, lies in their lack of selectivity. This means they are unable to distinguish between multiple trace gases unless more advanced methods like GC-MS or FTIR technology are employed. Unfortunately, these advanced methods are both bulky and expensive, restricting their usage to laboratory environments only. Quantum Cascade Laser (QCL), High sensitivity, Multi gases, Spectroscopy, Sensing system Electronics, Lasers, Optics & Photonics, Infocomm, Artificial Intelligence, Green Building, Indoor Environment Quality, Environment, Clean Air & Water, Sensor, Network, Monitoring & Quality Control Systems