Post Harvest Agriculture Protection using Microbiome Engineering


Life Sciences - Agriculture & Aquaculture
Life Sciences - Biotech Research Reagents & Tools


Post-harvest spoilage is a significant problem along the supply chain which results in great profit losses. Fungal infestation and mould growth are some of the common reasons for food waste and nutrition loss due to post-harvest degradation. Common post-harvest treatment includes unsustainable and excessive use of chemicals which can lead to contamination of the environment and our food.

Microbes associated with the plants and soil have co-evolved to confer beneficial traits to their plant counterparts. This technology relates to a highly effective and fully natural solution that exploits the plant microbiome for bio-based plant protection to increase the storability of fruits and vegetables. For example, the microbiome of microalgae can also be with beneficial microorganisms to increase the yield and reliability of algae growth in bioreactors. Moreover, microbiome tracking can be utilized to identify entry points of microbial contaminations.

This technology provider is seeking research collaboration with farmers to implement this solution for both soil-based and hydroponics agriculture. 



As a means to control post-harvest pathogens biologically, the native microbes of the targeted plant that confer protection against the pathogens are first screened. Afterwhich, the most promising candidates are tested for the benefits and against given pathogens in vitro. The best microorganisms will undergo field trials and successful candidates will be integrated directly into a seeding pill to convey this benefit to all plant offspring.

This technology can be further optimized for consistent effects, robust fermentation, and formulations with high shelf-life to develop a new generation of bio-based plant protection products.



This technology can be mainly applied to post-harvest protection of fruits and vegetables but can be extended to the following applications below:

  1. Plant protection - Engineering beneficial plant growth-promoting microbes into the microbiome of plants
  2. Microalgae photobioreactors - Engineering microalgae microbiome with beneficial microbes to increase yield and reliability of algae-growth
  3. Microbial protection - Using microbiome tracking to identify entry points of microbial contaminants

Market Trends & Opportunities

Many synthetic agrochemicals are toxic, and their prolonged use can cause health risks and environment damage. Furthermore, rising human population and urbanisation has led to a greater demand for food and lesser agricultural land. This has led to the rising inclination toward organic farming and the use of biopesticides.

Majority of understanding on microbiomes comes from the human gut microbiome. However, there has been an increasing understanding of plant-microbe interactions for improving crop performance and protection, and increasing interest in microbial technologies.

Researchers are looking into exploiting the symbiotic relationships found within the plant and soil microbiota for bio-based solutions, such as biocontrol, biostimulation and biofertilisers, to support the sustainable agriculture movement.


  1. Allows targeted plant microbiome engineering 
  2. Fully natural solution to post-harvest degradation by using the plant’s pre-existing microbiome
  3. Biologically control specific post-harvest pathogens, tailor-made solution
  4. Any IP developed in the project would fully belong to the investor/industrial partner
Eco-Friendly 3D Substrates from Recycled Raw Materials
Probiotic Encapsulation Technology for Long-Term Storage and Protection in Stomach Acid
Encapsulation of Living cells for Cell Therapy and Biotech
Water-Repellent Particles for Farming and Desalination System
Automated, Scalable Generation of 3D Cell Cultures by Novel Bioprinter
Sustainable Shrimp Caviar Production Method
Formulation for Shrimp Culling & Immunity Augmentation
Enzyme Engineering Platform for Fast and Sustainable Production of Ingredients
Aquatic Feed Enhancement using Microbiome Technology
Wavelength-selective Solar Photovoltaic System (WSPV) For Urban Rooftop Farming